Bio-Technology & Bio-Informatics

indexOBJECTIVES

  • To provide a platform for young minds to diverge and evolve profoundly in the arenas of Biosciences.
  • To promote Human resource development in the areas of Biotechnology & Bioinformatics by conducting Training programme.

MILESTONE

  • Post Graduate Programme (Biotechnology) – 2002
  • Post Graduate Diploma in Bioinformatics – 2004
  • Post Graduate Programme (Bioinformatics) – 2006
  • DBT-BIF funded – 2006 onwards to till date.
  • Ph.D. (Biotechnology) – 2007
  • M.Phil (Biotechnology) – 2008

FORMER HEAD

index111

Late. Dr. P. DAISY,M.Sc., M.Phil., Ph.D. (2002-2014)

Year

Positions held at Holy Cross College, Trichy.

1980-1998 Lecturer in Zoology
1998 onwards Reader in Zoology
1998-2001 Vice Principal  & Reader in Zoology
2004 onwards Co-ordinator– Department of Biotechnology & Bioinformatics
2009 onwards Associate Professor, Department of Zoology
2012 onwards Head, Department of Zoology
2012 onwards Co-ordinator– DBT-Star college
2012 onwards Co-ordinator– DST FIST
2012 onwards Research Co-ordinator– CPE
2012 onwards Overall Co-ordinator– Star College Scheme
2014 Dean of Science

 

FACULTY

S. No.

NAME

DESIGNATION

QUALIFICATION

SPECIALIZATION

1

Dr.M.Rajalakshmi

Assistant Professor in Zoology & Coordinator

M.Sc.,M.Phil.,Ph.D, PGDBI.

Phytotherapeutics and Computer aided drug designing

2

Ms. M.V.Sujitha

Assistant Professor

M.Sc., M.Phil, SLET., (Ph.D).

Cancer Biology

3

Ms. A. Anita Roy

Assistant Professor

M.Sc., (Ph.D.).

Cancer Biology

 RESEARCH FACULTY: DBT-BIF CENTRE

1. Dr.M.Rajalakshmi Co-ordinator M.Sc.,M.Phil.,Ph.D,

PGDBI.

Phytotherapeutics and Computer aided drug designing
2. Ms.A.Anita Roy Research Assistant

(Part-time)

M.Sc., (Ph.D.). Cancer Biology & CADD

3.

Ms.A.Ludas Trainee M.Sc., (Ph.D.).

Cancer Biology & CADD

4.

Ms.Jasminenathesa Studentship M.Sc., (M.Phil)

Stem cell therapy & CADD

 

DEPARTMENT ACTIVITIES

ACTIVITIES & DATE

RESEOURCE PERSONS

TITLE

2015-2016

Association Inauguration

10/06/2014

Dr. S. Subhashini, Assistant Professor of Biotechnology, Faculty of Engineering & Technology, SRM University, Chennai

Preclinical studies on phytochemical, wound healing and antigenotoxic properties of Indian Medicinal plants’

One day orientation programme

15/06/2014

Rev. Sr. Mary Selesty Sales, Provincial, St.Annne’s Convent, Tanjore,

Rooted in goodness through excellence

One day interdepartmental Competitions

01/09/2015

Faculty of the department

BIOUTSAV’ 15

Workshop for final year U.G. Life Science students

6th – 7th Jan 2016

Dr.M.Rajalakshmi,

Co-ortinator, DBT-BIF Centre, HCC, Trichy

Faculty of the Centre & the Department

Basics of Bioinformatics

Alumnae Meet

23rd Jan 2016

Dr.Sujatha Elangovan

Assistant Professor of Zoology, HCC, Trichy.

Scope of Biotechnology in the present scenario

2014-2015

Association Inauguration

24/06/2014

S. Parthasarathy, Head and Associate Professor, Dept of Bioinformatics, Bharathidasan University, Trichy

DNA Barcoding

Invited lecture

31/07/2014

Mr.R.Ragu, Vice-President, Schrodinger

“Success story in designing inhibitors for IRAK4 and ACC using

Docking and Hydration site thermodynamics”

3 day Workshop cum Training

12th–14th August 2014

Faculty of BIF-Centre & Department

“Basics of Bioinformatics & CADD”

One day colloquium

 

Tribute to Late. Dr.P.Daisy

ØRelease of a CD of Dr.Daisy’s contribution

ØRelease of book on “Research on Phytotherapeutic Approach towards Drug Designing” – A compilation of Dr.Daisy’s 83 research papers

ØIndroduction of Dr.P.Daisy Endowment of Rs.2 lakhs.

 

27th August 2014

Dr.T.Madhan Mohan, Advisor, Department of Biotechnology, Government of India, New Delhi

Integrative Biology

Dr. Oommen V. Oommen, Professor, CSIR Emeritus Scientist and Chairman, Kerala Biodiversity Board, Trivandrum.
Dr.T.Sivanandappa,Emeritus Scientist, Department of Studies in Zoology, University of Mysore.
Dr.M.Michael Aruldhas, Retd. Professor and Head, Department of Endocrinology, Dr.ALMPGIBMS, University of Madras, Taramani, Chennai.
Invited lecture

20/10/2014

Dr.Maneesh Mailankot, Pushpagiri Research Institute, Kerala

Metabolic basis of inflammatory cytokines mediated cytotoxicity

National workshop on “In-silico Drug Designing approach

5th -7th Nov 2014

Dr.M.Rajalakshmi,

Co-ortinator, DBT-BIF Centre, HCC, Trichy

Faculty of the Centre & the Department

In-silicoDrug Designing approach

Association Valediction

10/02/2015

Dr. Damodharan Bakkiyaraj, Research Associate, Department of Microbiology, Bharathidasan University, Tiruchirapalli

Can Bacteria talk?”

Alumnae meet

14/02/2015

Ms.Saranya, PRM Associate, Icon Clinical Research, Chennai

Opportunities for Life Science graduates in clinical research

PATENTS

Patents granted to Late. Dr.P.Daisy: 2

Patent No.:244666

Title of the invention :A process for preparation of a novel compound, 5,6-dihydroxy-3-[(4-hydroxy-6(hydroxymethyl) 3,5-DI[3,4,5-trihydroxy-6-(hydroxymethyl) tetrahydro-2H-2pyranyl] oxytetrahydro-2H-2-pyranyl)oxy] -2-methoxy-10, 13- imethylperhydrocyclopenta [?] phenanthren-17-yl (phenyl)methylacetate from Syzygium cumini (l) skeels, seeds with antibacterial and antidiabetic activity.

Patent No.:246537

Title of the invention:A process for preparation of a novel compound Gymnemic triacetate from Gymnema sylvestre R. BR.leaves with antidiabetic activity.

Patents Filed (Late. Dr.P.Daisy & Dr.M.Rajalakshmi): 8

i.  A process for preparation of a novel compound Terpenoid from Elephantopus scaber (809/CHE/2007)
 ii. A process for preparation of a novel compound Dihydroxy Gymnemic triacetate from Gymnema sylvestre (1653/CHE/2007).
iii. A process for preparation of a novel compound Gymnemic diacetate from Gymnema sylvestre (1652/CHE/2007)
iv. A process for preparation of a novel compound17-[(E)-4-ethyl-1’,5’-dimethyl-2’-hexenyl]-11-hydroxy-5-(hydroxymethyl)13,14-dimethyl-5,6,7,11,12,13,14,15, 16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one from Cassia fistula
v. A process for preparation of a novel compound17-[(E)-1’,5’-dimethyl-2’-hexenyl]-11-hydroxy-5-(hydroxymethyl)-13,14-dimethyl-5,6,7,11,12,13,14, 15, 16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one from Cassia fistula
vi. A process for preparation of a novel compound17-[(2E,5E)-4’,7’-diethyl-1’,8’-dimethyl-2’,5’-nonadienyl]-11-hydroxy-5-(hydroxymethyl)-13,14-dimethyl-5,6,7,11,12,13,14,15,16,17-decahydro-3H cyclopenta [a] phenanthren-3-one fromCassia fistula
vii. A process for preparation of a novel compound 7-(4-hydrdoxy-9,10-dioxo-9,10-dihyroanthracen-2yl)-3-methylept-2-enoic acid  from Cassia auriculata stem bark with anti-diabetic property.
viii. A process for preparation of a novel polysaccharide from methanol extract of Tinospora cordifolia stem with anti-diabetic property

 

ACHIVEMENTS: ACADEMIC/ NON ACADEMIC

FACULTY MEMBERS

Dr.M.Rajalakshmi MRE Awardfrom Society of Reproductive Biology & Comparative Endocrinology
Database created : DaiCee database for identification of targets and side-effects of cancer drugs
Prof N J Chinoy best Paper Awardof SRBCE, International Conference  January,2009
Late. Dr.P.Daisy & Dr.M.Rajalakshmi Database created

DIAB 1– www.hccbif.org– Compilation of different Medicinal Plants for their Antidiabetic, Antimicrobial and Antioxidant properties.

DIAB 2– www.hccbif.info–  Collection of Pharmacophore Analysis of 175 active principles from the medicinal plants for Antidiabetic, Antioxidant, Antimicrobial and Anticancerous effects and their docking studies.

Ms.A.Anita Roy Prof N J Chinoy best Paper Awardof SRBCE and also the Gold Medal Best Young Scientist from Holy Cross College

DBT-BIF CENTRE

INCENTIVE AWARD of Rs.5 lakhs for her best research publication among the colleges with BIF-Centre in India (2013-2014).

STUDENTS

Ms. A.Clara Mary, M.Sc.Biotechnology ·  Poetry writing, BDU Fest, Bharathidasan University, Trichy

·  Poetry writing, Wild life Celebration, Department of Zoology, Holy Cross College, Trichy.

Ms.S.Hinduja, M.Sc.Biotechnology

Ms.Harshini, M.Sc.Biotechnology

·  Rangoli, Wild life Celebration, Department of Zoology, Holy Cross College, Trichy.

 

RANK HOLDERS & BEST OUTGONE

Year

M.Sc. Biotechnology

University rank

M.Sc. Bioinformatics

University rank

2006-8 K.Sudha

II

D.Hema

III

2007-9 S.N. Rajashree

I

S.Umamaheswari

III

2008-10 D.Geethalakshmi

IV

P.Subhashini

III

2009-11 A.Anita Roy

IV

A.Sherlin Rosita

II

2010-12 G.Suganya

III

A.Kavitha

Best outgone

2011-13 J.Angela Lincy

I

Sumayaparveen

Best outgone

2012-14 G.Gomathi

V

Edel Usha

Best outgone

2013-15 Sharmila Devi

III

I.Justina Princy

Best outgone

 

INNOVATIVE TEACHING AND LEARNING METHODS

E-Lessons

Videos

Animations

Powerpoint presentations

Mind maps

Models

Debates

Smart board

 

NUMBER OF E-LESSONS DEVELOPED:10

MAJOR/MINOR PROJECTS

STAFF

PROJECT

YEAR

Late . Dr.P.Daisy UGC Major-Evaluation of some plant extracts for antidiabetic effect

2001-2004

Late. Dr.P.Daisy UGC Major-Identification and characterization of active principles in a few medicinal plants for diabetes

2007-2010

Late. Dr.P.Daisy

Dr.M.Rajalakshmi

UGC Major-Evaluating the impact of five active principles from five different medicinal plants on activated cancer animals and cell-lines

2012-2015

Dr.M.Rajalakshmi UGC Minor-Exploring the anticancer efficacy of a polysaccharide (4832/CHE/2012) isolated and identified from methanol extract of Tinospora cordifolia in-vitro, in-vivo and in-silico approach

2014-2016

DBT-BIF Centre Infrastructure facility fund

2006 onwards

 

RESEARCH DETAILS

S.

No

Name of Research guides

Ph.D

M.Phil

Scholars produced

Pursuing

Scholars Produced

Pursuing

1. Late.Dr.P.Daisy

10

35

2. Dr.M.Rajalakshmi

2

7

26

3

3. Dr. Cecily Rosemary Latha

1

2

1

 

MOUs

International tie-ups for research/MOU’s:

  • Dr.Thameem Dheen, National University of Singapore. Singapore.
  • Dr. Antonietta La.Terza, University of Camerino. Italy.
  • Dr. Arun Dharmarajan, School of Anatomy and Physiology, Western University of Australia.
  • Dr. Shakila. K. Banu, Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A& M University, TX, USA, for the promotion of Research and Advancement.
  • Dr. G. Agaramoorthy, Tajen University, Taiwan.

National tie-ups for research:

  • Dr.P.Yogitha Shristi Biosciences Ltd, Hyderabad.
  • Dr.Maneesh Mailankot, Scientist, Pushpagiri Research Centre Pushpagiri Institute of Medical Sciences Thiruvalla, Kerala.
  • Dr. V.R. Ravi (MS Ortho), Mother Cell Regenerative Centre – PVT. Ltd, Trichy.
  • Dr.K.Balasunramanian, Professor, Department of Endocrinology, Dr.A.L.M.P.G.I.B.M.S, University of Madras, Chennai.
  • Dr.J.Arunakaran, Associate professor Department of Endocrinology, Dr.A.L.M.P.G.I.B.M.S, University of Madras, Chennai.
  • Dr.Sanjeev Kumar Singh, Associate Professor Department of Bioinformatics, Alagappa University, Karaikudi.
  • MOU with Solai Ayurvedics, Vellore, to carry out clinical trials as a part of the research activity.  Centre for Research in Entomology, Loyola College, Chennai.
  • Dr.D.Velmurugan, Head, Center for Advanced Study in Crystallography and Biophysics
  • Dr.R.Rajashekaran, Assistant professor, Bioinformatics Division, VIT, Vellore.

STUDENT CENTRED SERVICES

    • DBT-BIF Centre – Training programme on Bioinformatics for students from India and abroad
    • Two students from Africa were given training on ‘Tools in Bioinformatics’.
    • Training in ‘Basic computational tools for drug designing’ to student from SASTRA University, Tanjavur.
    • Workshop on ‘Basics of Bioinformatics’ for Life Science students of Holy Cross College.

DISTINGUISHED ALUMNI

Dr. Anju George, CCMB, Hyderabad
Dr. Nirmala Arul Rayan, PDF, ?Genome Institute of Singapore, Singapore.
Dr. Dhivyavadhana, PDF, New Jersey, USA.
Dr.Pricilla, PDF, Germany.
Dr. Nimmy Baby, National University of Singapore.
Dr. P. Ambika, Australia.
Ms. G. Deepika, Food Corporation, Coimbatore.
Ms.G.Vijayalakshmi, Ph.D., Korea.